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Obesitas type 1

105 Worldwide there has been a large shift towards less physically demanding work, and currently at least 30 of the world's population gets insufficient exercise. 107 This is primarily due to increasing use of mechanized transportation and a greater prevalence of labor-saving technology in the home. In children, there appear to be declines in levels of physical activity due to less walking and physical education. 109 World trends in active leisure time physical activity are less clear. The world health Organization indicates people worldwide are taking up less active recreational pursuits, while a study from Finland 110 found an increase and a study from the United States found leisure-time physical activity has not changed significantly. 111 A 2011 review of physical activity in children found that it may not be a significant contributor. 112 In both children and adults, there is an association between television viewing time and the risk of obesity. A review found 63 of 73 studies (86) showed an increased rate of childhood obesity with increased media exposure, with rates increasing proportionally to time spent watching television. 116 Genetics main article: Genetics of obesity like many other medical conditions, obesity is the result of an interplay between genetic and environmental factors. 118 Polymorphisms in various genes controlling appetite and metabolism predispose to obesity when sufficient food energy is present. As of 2006, more than 41 of these sites on the human genome have been linked to the development of obesity when a favorable environment is present.

obesitas type 1

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For women, the average increase was 335 calories (1,400 kJ) per day (1,542 calories (6,450 kJ) in 1971 and 1,877 calories (7,850 kJ) in 2004 while for men the average increase was 168 calories (700 kJ) per day (2,450 calories (10,300 kJ) in 1971 and 2,618 calories (10,950 kJ) in 2004). Most of this extra food koolhydraten energy came from an increase in carbohydrate consumption rather than fat consumption. 93 The primary sources of these extra carbohydrates are sweetened beverages, which now account for almost 25 percent of daily food energy in young adults in America, 94 and potato chips. 95 Consumption of sweetened drinks such as soft drinks, fruit drinks, iced tea, and energy and vitamin water drinks is believed to be contributing to the rising rates of obesity 96 97 and to an increased risk of metabolic syndrome and type 2 diabetes. 98 Vitamin D deficiency is related to diseases associated with obesity. 99 As societies become increasingly reliant on energy-dense, big-portions, and fast-food meals, the association between fast-food consumption and obesity becomes touwspringen more concerning. 100 In the United States consumption of fast-food meals tripled and food energy intake from these meals quadrupled between 19101 Agricultural policy and techniques in the United States and Europe have led to lower food prices. In the United States, subsidization of corn, soy, wheat, and rice through the. Farm bill has made the main sources of processed food cheap compared to fruits and vegetables. 102 Calorie count laws and nutrition facts labels attempt to steer people toward making healthier food choices, including awareness of how much food energy is being consumed. Obese people consistently under-report their food consumption as compared to people of normal weight. 103 This is supported both by tests of people carried out in a calorimeter room 104 and by direct observation. Sedentary lifestyle see also: Sedentary lifestyle and Exercise trends A sedentary lifestyle plays a significant role in obesity.

obesitas type 1

2,0002,200 (8,4009,200) 2,2002,400 (9,20010,000) 2,4002,600. 87 dietary energy supply per capita varies markedly between different regions and countries. It has also changed significantly over time. 86 From the early 1970s to the late 1990s the average food energy available per person per day (the amount of food bought) increased in all parts of the world except Eastern Europe. The United States had the highest availability with 3,654 calories (15,290 kJ) per person in 1996. 86 This increased further in 2003 to 3,754 calories (15,710 kJ). 86 During the late 1990s Europeans had 3,394 calories (14,200 kJ) per person, in the developing areas of Asia there were 2,648 calories (11,080 kJ) per person, and in sub-Saharan Africa people had 2,176 calories (9,100 kJ) per person. 86 88 Total food energy consumption has been found to be related to obesity. 89 The widespread availability of nutritional guidelines 90 has done little to address the problems of overeating and poor dietary choice. to 2000, obesity rates in the United States increased from.5.9. 92 During the same period, an increase occurred in the average amount of food energy consumed.

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People with class i obesity and heart disease do not have greater rates of further heart problems than people of normal weight who also have heart disease. In people with greater degrees of obesity, however, the risk of further cardiovascular events is increased. 77 78 even after cardiac bypass surgery, no increase in mortality is seen in the overweight and obese. 79 One study found that the improved survival could be explained by the more recepten aggressive treatment obese people receive after a cardiac event. 80 Another found that if one takes into account chronic obstructive pulmonary disease (copd) in those with pad, the benefit of obesity no longer exists. 75 causes At an individual level, a combination of excessive food energy intake and a lack of physical activity is thought to explain most cases of obesity. 81 A limited number of cases are due primarily to genetics, medical reasons, or psychiatric illness. 9 In contrast, increasing rates of obesity at a societal level are felt to be due to an easily accessible and palatable diet, 82 increased reliance on cars, and mechanized manufacturing. 83 84 A 2006 review identified ten other possible contributors to the recent increase of obesity: (1) insufficient sleep, (2) endocrine disruptors (environmental pollutants that interfere with lipid metabolism (3) decreased variability in ambient temperature, (4) decreased rates of smoking, because smoking suppresses appetite, (5). 85 While there is evidence supporting the influence of these mechanisms on the increased prevalence of obesity, the evidence is still inconclusive, and the authors state gerechten that these are probably less influential than the ones discussed in the previous paragraph.

obesitas type 1

The strength of the link between obesity and specific conditions varies. One of the strongest is the link with type 2 diabetes. Excess body fat underlies 64 of cases of diabetes in men and 77 of cases in women. 48 health consequences fall into two broad categories: those attributable to the effects of increased fat mass (such as osteoarthritis, obstructive sleep apnea, social stigmatization) and those due to the increased number of fat cells ( diabetes, cancer, cardiovascular disease, non-alcoholic fatty liver disease ). 2 49 Increases in body fat alter the body's response to insulin, potentially leading to insulin resistance. Increased fat also creates a proinflammatory state, 50 51 and a prothrombotic state. 49 52 Survival paradox see also: Obesity paradox Although the negative health consequences of obesity in the general population are well supported by the available evidence, health outcomes in certain subgroups seem to be improved at an increased bmi, a phenomenon known as the obesity. 74 The paradox was first described in 1999 in overweight and obese people undergoing hemodialysis, 74 and has subsequently been found in those with heart failure and peripheral artery disease (PAD). 75 In people with heart failure, those with a bmi between.0 and.9 had lower mortality than those with a normal weight. This has been attributed to the fact that people often lose weight as they become progressively more ill. 76 Similar findings have been made in other types of heart disease.

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38 39 This appears to apply in at least four continents. 37 In contrast, a 2013 review found that grade 1 obesity (bmi 3035) was not associated with higher mortality than normal weight, and that overweight (bmi 2530) was associated with "lower" mortality than was normal weight (bmi.525). 40 Other evidence suggests that the association of bmi and waist circumference with mortality is u- or J-shaped, while the association between waist-to-hip ratio and waist-to-height ratio with mortality is more positive. 41 In Asians the risk of negative health effects begins to increase between 2225 kg/m2. 42 a bmi above 32 kg/m2 has been associated with a doubled mortality rate among women over a 16-year period. 43 In the United States, obesity is estimated to cause 111,909 to 365,000 deaths per year, snel 2 34 while 1 million (7.7) of deaths in Europe are attributed to excess weight. 44 45 On average, obesity reduces life expectancy by six to seven years, 2 46 a bmi of 3035 kg/m2 reduces life expectancy by two to four years, 36 while severe obesity (BMI 40 kg/m2) reduces life expectancy by ten years. 36 Morbidity main article: Obesity-associated morbidity Obesity increases the risk of many physical and mental conditions. These comorbidities are most commonly shown in metabolic syndrome, 2 a combination of medical disorders which includes: diabetes mellitus type 2, high blood pressure, high blood cholesterol, and high triglyceride levels. 47 Complications are either directly caused by obesity or indirectly related through mechanisms sharing a common cause such as a poor diet or a sedentary lifestyle. obesitas type 1

25 The most commonly used definitions, established by the world health Organization (WHO) in 1997 and published in 2000, provide the values listed in the table. 26 alvleesklier 27 Some modifications to the who definitions have been made by particular organizations. 28 The surgical literature breaks down class ii and iii obesity into further categories whose exact values are still disputed. 29 Any bmi 35 or 40 kg/m2 is severe obesity. A bmi of 35 kg/m2 and experiencing obesity-related health conditions or 4044.9 kg/m2 is morbid obesity. A bmi of 45 or 50 kg/m2 is super obesity. As Asian populations develop negative health consequences at a lower bmi than caucasians, some nations have redefined obesity; Japan have defined obesity as any bmi greater than 25 kg/m2 8 while China uses a bmi of greater than 28 kg/m2. 28 Effects on health Excessive body weight is associated with various diseases and conditions, particularly cardiovascular diseases, diabetes mellitus type 2, obstructive sleep apnea, certain types of cancer, osteoarthritis 2 and asthma. 2 30 As a result, obesity has been found to reduce life expectancy. 2 Mortality relative risk of death berekenen over 10 years for white men (left) and women (right) who have never smoked in the United States by bmi. 31 Obesity is one of the leading preventable causes of death worldwide. A number of reviews have found that mortality risk is lowest at a bmi of 2025 kg/m in non-smokers and at 2427 kg/m2 in current smokers, with risk increasing along with changes in either direction.

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He presents with stretch marks and enlarged breasts Obesity is a medical condition in which excess body fat has accumulated to the extent that it may have an adverse effect on health. 19 It is defined by body mass index (BMI) and further evaluated in terms of fat distribution via the waisthip ratio and total cardiovascular risk factors. 20 21 bmi is closely related to both percentage body fat and total body fat. 22 In children, a healthy weight varies with age and sex. Obesity in children and adolescents is defined not as an absolute number but in relation to a historical normal group, such that obesity is a bmi greater than the 95th percentile. 23 The reference data on which these percentiles were based date from 1963 to 1994, and thus have not been affected by the recent increases in weight. 24 bmi is defined as the subject's weight divided by the square of their height and is calculated as follows. Bmimh2displaystyle mathrm bmi frac mh2, where m and h are the subject's weight and height respectively. Bmi is usually expressed in kilograms per square metre, resulting when weight is measured in kilograms and height in metres. To vlees convert from pounds per square inch multiply by 703 (kg/m2 lb/sq in).

obesitas type 1

2 diet quality can be improved by reducing the consumption of energy-dense foods, such as those high in fat or sugars, and notariskosten by increasing the intake of dietary fiber. 1 Medications kaartjes can be used, along with a suitable diet, to reduce appetite or decrease fat absorption. 5 If diet, exercise, and medication are not effective, a gastric balloon or surgery may be performed to reduce stomach volume or length of the intestines, leading to feeling full earlier or a reduced ability to absorb nutrients from food. 6 12 Obesity is a leading preventable cause of death worldwide, with increasing rates in adults and children. 1 13 In 2015, 600 million adults (12) and 100 million children were obese in 195 countries. 7 Obesity is more common in women than men. 1 Authorities view it as one of the most serious public health problems of the 21st century. 14 Obesity is stigmatized in much of the modern world (particularly in the western world though it was seen as a symbol of wealth and fertility at other times in history and still is in some parts of the world. 2 15 In 2013, the American Medical Association classified obesity as a disease. 17 Contents Classification main article: Classification of obesity bmi (kg/m2) Classification 18 from up.5 underweight.5.0 normal weight.0.0 overweight.0.0 class i obesity.0.0 class ii obesity.0 class iii obesity a "super obese" male with a bmi.

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For the medical journal, see, obesity (journal). Obesity is a medical condition in which excess body fat has accumulated to the extent that it may have a negative effect on health. 1, people are generally considered obese when their body mass index (bmi a measurement obtained by dividing a person's weight by the square of the person's height, is over kg / standaard m2, with the range kg / m2 defined as overweight. Some, east Asian countries use lower values. 8, obesity increases the likelihood of various diseases and conditions, particularly cardiovascular diseases, type 2 diabetes, obstructive sleep apnea, certain types of cancer, osteoarthritis and depression. 2 3, obesity is most commonly caused by a combination of excessive food intake, lack of physical activity, and genetic susceptibility. 1 4 A few cases are caused primarily by genes, endocrine disorders, medications, or nutrilon mental disorder. 9 The view that obese people eat little yet gain weight due to a slow metabolism is not generally supported. 10 On average, obese people have a greater energy expenditure than their normal counterparts due to the energy required to maintain an increased body mass. 10 11 Obesity is mostly preventable through a combination of social changes and personal choices. 1 Changes to diet and exercising are the main treatments.

Obesitas type 1
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obesitas type 1 Ratoky, Sun, May, 06, 2018

14 (Healthdaynews) - scientists know that obesity is a key player in the development of type 2 diabetes, but exactly how excess weight causes the disease isn't clear. While trying to answer that question, harvard University researchers have discovered a new pathway that sets in motion a series of reactions that leads to the development of insulin resistance, a precursor of type 2 diabetes, a new study reports. The researchers found that obesity causes stress in a system of cellular membranes called endoplasmic reticulum (er which in turn causes the endoplasmic reticulum to suppress the signals of insulin receptors, which then leads to insulin resistance.

obesitas type 1 Epyzo, Sun, May, 06, 2018

Comment: Research into diabetes today is far ranging. It ranges from the environment to the deep dark recesses of the single cell. It is much easier to look at the environment, for example, "Super size me" in a fast-food culture, than it is to sort out what is going on inside the workings of an individual cell. Medical Editors, m, study suggests How Obesity causes diabetes. By serena gordon, healthday reporter, thursday, oct.

obesitas type 1 Iselih, Sun, May, 06, 2018

Specifically, overeating stresses the membranous network inside of cells called endoplasmic reticulum (ER). When the er has more nutrients to process than it can handle, it sends out an alarm signal telling the cell to dampen down the insulin receptors on the cell surface. This translates to insulin resistance and to persistently high concentrations of the sugar glucose in the blood - one of the sure signs of diabetes.

obesitas type 1 Kiketec, Sun, May, 06, 2018

Being overweight or obese increases the chances of developing the common type of diabetes, type 2 diabetes. In this disease, the body makes enough insulin but the cells in the body have become resistant to the salutary action of insulin. Why does this happen? Latest diabetes News, new Research: A report this week in Science proposes that being overweight stresses the insides of individual cells.

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